Bisphenol A (BPA) is a man-made chemical used in manufacturing a wide range of commonly consumer products. This study reports on the dietary exposure of adults people in Yaoundé, Cameroon to BPA. One hundred and thirty water, soft drink and table-ready food samples were collected from households and street restaurants and analyzed for BPA contents using enzyme-linked immunosorbent assay. BPA (range, 0.007-52 ng.g-1) was detected in 99.23% of samples. BPA concentrations in 66.66% canned foods and 12.5% foods in plastic containers were above the specific migration limit established by the European Food Safety Authority (EFSA).The mean concentrations of BPA in water, soft drink and food group samples were 10.39; 1.017 and 13.45 ng.g-1 respectively. The highest average daily intakes (ADIs) of BPA in respective categories were through tap water (72 µg.day-1), bottle soft drink (0.231 µg.day-1) and rice food-base mixed dishes (2638.8 µg day-1) consumption. The estimated average daily exposure doses (ADED) with respect to gender (women, 0.498 µg.kg-1 body weight day-1; men, 0.658 µg.kg-1 bw.day-1), professional status (range, 0.56-0.84 µg.kg-1 bw.day-1) and in the sample of population studied (0.622 µg.kg-1 bw.day-1) were below the provisional tolerable daily intake (PTDI). The highest ADED (3.591 µg.kg-1 bw.day-1) in the population, represented 89.77% of the PTDI. Nevertheless, as an endocrine disruptor, the margin of exposure ˂ 100, indicates health risk concern associated with continuous ingestion of such contaminated beverages and foods. The data of this first report in Central Africa, speculate need for awareness towards reducing exposure levels of BPA in Cameroon.