COVID-19 is a virus with its dimensions of about 100 nm when is in its spherical shape, had proven remarkable features as a nano-bot with displacement capabilities performed by spikes, a protein shield, and inside a genetic code, programmed to hack the cells and uses to reproduce itself. Duet to its shield and affinity for water it has proven a good immunity to environmental chemical agents, conferring it long survival time in air and surfaces. A very interesting feature is its affinity for human body, where it develops seamless, the human carrier becoming contagious well before realizing that is sick, and seek medical cure. Virus appeared in disputed circumstances in China, and in just 2 months spread on entire world, which was really unprepared and uneducated to face this entity, ending up with many causalities and a huge economic impact estimated at about ¼ GDP of most of the affected countries. From technological point of view, there are very limited ways to stop the virus and reduce the contamination, and a nano-technologic approach and understanding is needed to solve this problem that to guide social, behavioral and medical efforts both for seeking a cures and for individual protection.