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Ramamoorthy KOKILA, Rangaraj SURIYAPRABHA, Subramani KARTHIK, Gopal NANDHINI, Venkatachalam RAJENDRAN; Antibacterial and Antioxidant Potential of Herbal Nanoparticles Produced from the Shells of Jatropha Curcas; Advanced Nano-Bio-Materials and Devices; 2017:1(1):39-47
Shells of Jatorpha curcas is commonly used as fuel and as soil fertilizer. In our study, we investigate the use of shells to synthesize nanoscale particles by mechanical grinding via top down approach. The shade-dried shells are subjected to high energy milling to produce nanoparticles and the collected powder is characterized for their particle size, crystallinity, functional group and elemental composition. Antimicrobial activity of the prepared nanoparticles reveals the significant inhibitory effect against Gram positive bacteria (S. aureus and S. epidermis) and gram negative bacteria (E. coli and K. pneumoniae). Growth of gram positive organism is found to be reduced by 50-60 % when the particle size is increased from 1 to 20 mg/ml whereas gram negative bacteria has 30-45 % of growth reduction. When compared to control, shell nanoparticles exhibit an excellent antioxidant activity about at 78 % at 20 mg/ml against DPPH reagent. This preliminary evaluation for the bioactivity of shell nanoparticles from Jatropha lead the future biorefinery processing of Jatropha plant materials into cost effective biological product development.