Remus NESTOR, Alexandru BACANU, Gabriel MIHALCEA, Alexandru TiRLUNGEANU; A Review of the Transistors with Organic Semiconductor used in the Biosensor Fabrication. Advanced Nano-Bio-Materials and Devices; 2023:7(4):745-754

Semiconductor transistors are increasingly being used in biosensors due to their ability to detect biological molecules with high sensitivity and selectivity. These biosensors typically operate based on the modulation of charge carrier transport through the transistor channel in response to the presence of a specific biological molecule, resulting in a measurable electrical signal. This approach offers several advantages over traditional sensing methods, including high sensitivity, selectivity, and real-time monitoring capabilities. This paper discusses an overview of the working principle, technology development, and performance development of transistors with organic semiconductor applied in biosensors, highlighting the potential of these devices in the development of novel flexible biosensing platforms for a large range of applications in the medical diagnostics, environmental monitoring, and food safety.